1996 - 1998

Engineer-researcher of the Laboratory of biophysics of active media, ITEB RAS

Senior Laboratory Assistant at the Laboratory of neuron mechanisms of plastic processes, Institute for Brain, Russian Academy of Medical Sciences.

Research project:
Linear, nonlinear and chaotic phenomena in modeling of the ventricular arrhythmias.
Organization:
Institute of Mathematical Problems of Biology, Russian Academy of Sciences.
Responsibilities:
- coordinate the Project;
- the general design of the investigation;
- software development;
- data processing.
Accomplishments:
You can visit my web-report 'My scientific activity' to trace current state of the work.

Research project:
Investigation of the ventricular arrhythmias in silico and in vitro.
Organization:
Institute of Theoretical and Experimental Biophysics, Russian Academy of Sciences.
Responsibilities:
- coordinate the Project;
- data processing.
Accomplishments:
- nonlinear effects of lidocaine on polymorphism of ventricular arrhythmias was corroborated;
- a scientific paper was published;
- two chapters for a book were contributed, one of them was published.

Research project:
Analysis of transformed electrocardiograms: development of new non-invasive procedures of evaluation of the cardiac activity and the state of cardiac tissue.
Organization:
Institute of Theoretical and Experimental Biophysics, Russian Academy of Sciences.
Responsibilities:
- coordinate the Project;
- data processing.
The Project is a part of the Institute research program "Cellular and Tissue Bio-Synergetic..." with State Registration Number 01.0.40002202.
Accomplishments:
- a new type of spiral wave behavior was discovered;
- a new mechanism of spontaneous transition from polymorphic to monomorphic arrhythmia was described;
- a mathematical approach to quantitative analysis of motion of a spiral wave tip was developed;
- four scientific paper were published and two more scientific papers were submitted.

Please, visit section Cybernetic and Biophysical Cardiology.

2001-2002

Name of project:
http://cbp.iteb.psn.ru/AVM/ library web-site.
Organization:
Central Library of Pushchino Science Center, Russian Academy of Sciences.
Responsibilities:
- taking part in working out the site conception;
- design, graphics, making-up, client-side scripts, support;
- correcting of an existing database programs.
Tools:
NotePad, CoffeCup HTML Editor, PhotoShop5.5, ImageReady, CoffeCup Gif Animator, MS FP Personal server.
Accomplishments:
- took part in analysis of requirements and conception;
- designed all pages;
- drew and edited pictures, using Adobe PhotoShop;
- implemented web-site, using FrontPage web application server and NoteBook.

Research project:
Investigation for finding integral parameters that could characterize ECG during polymorphic ventricular tachycardia.
Organization:
Institute of Theoretical and Experimental Biophysics, Russian Academy of Sciences.
Responsibilities:
- data processing.
Accomplishments:
- a new approach for ECG analysis were invented;
- two scientific papers were published.

1999-2000

Name of project:
Laboratory web-site: http://WWW.ITEB.RU/BAM/
Organization:
Institute of Theoretical and Experimental Biophysics, Russian Academy of Sciences.
Responsibilities:
design, graphics, making-up, client-side scripts.
Tools:
MS FrontPage, Adobe PhotoShop, MS FP Personal server.
Accomplishments:
- took part in analysis of requirements and conception;
- designed all pages;
- drew and edited pictures, using Adobe PhotoShop;
- implemented http://WWW.ITEB.RU/BAM/ laboratory web-site, using FrontPage web application server and JavaScript editors.
(the project was suspended due to the circumstances of the client).

Research project:
Experimental mapping studies of the mechanisms of cardiac arrhythmia in isolated cardiac muscle preparations.
Organization:
Institute of Theoretical and Experimental Biophysics, Russian Academy of Sciences.
The general objective of this project was to investigate evolution and mechanisms of spatio-temporal excitation patterns typical of cardiac rhythm disturbances.
Responsibilities:
- planing and carriing out the experiments.

1997-1999

Software engineering project:
Automated working place for physiologist-researcher.
Organization:
Institute of Theoretical and Experimental Biophysics, Russian Academy of Sciences.
Responsibilities:
full application development life cycle: analyzed, designed, developed, tested the project for distributed computer system of the IBM-PC and L1250-device (L-card Ltd.) built on the base the signal microcomputer ADSP2105.
Tools:
Delphi, Assembler, ADSP-2100 microcomputer family Assembler tools (Analog Devices Inc.).
Accomplishments:
This project is intended for servicing the control and data acquisition needs of a multi-electrode mapping system for physiological investigations. I myself developed the software for the automated workplace for scientist researcher.
Hardware was a distributed computer system consisted of the IBM-PC and L1250-device built on the base the signal microcomputer ADSP2105 family. The computers interacted through the ISA-slot. Under program control, such a system maintains both high-rate data registration and electrical stimulation of investigated physiological object in real time. Using ADSP-2100 family Assembler tools (Analog Devices Inc.), I wrote the program for ADSP2105 in Assembler for ADSP2105; this program maintains a circular FIFO-buffer in order protection against the data loss.
(See code example)
The programs for the PC were written in Object Pascal using the integrated instrumental environment Delphi, and a part of the application for the PC was written in integrated Assembler. Program package for PC includes the means for the computer visualization obtained data as well as the means for automatic experiment protocol keeping.
(See code example)
This project is intended for servicing of the plant for multi-electrode mapping of myocardium used for physiological investigations.

1996-1997

Software developing project:
Implementation of Hodgkin-Huxley model of membrane potential (Supervisor: Prof. Dr A. B. Medvinsky)
Organization:
Institute of Theoretical and Experimental Biophysics, Russian Academy of Sciences.
Tools:
Turbo C 2.x, Turbo Debugger for MS-DOS.
Accomplishments:
Participated in a project of digital modelling. My part of this work was to release the physiological non-distributed model of membrane potential by Hodgkin-Huxley. Programming in C++ language.

1994-1995

Undergraduate software developing project:
Consulting system for gynaecologist using mathematical model of endocrine regulation of the follicular phase of menstrual period (Head: Dr V.V. Kilekovsky)
Organization:
Russian State Medical University.
Tools:
Visual Basic.
Accomplishments:
Worked out beta-version of the consulting system for gynaecologist: design, development, testing.

1993

Organization:
Russian State Medical University.
Tools:
Assembler for IBM-mainframe.
Accomplishments:
Developed a small application to familiarize myself with Assembler for IBM-mainframe.

Student research work:
Organization:
Laboratory of neuron mechanisms of plastic processes, Institute of Brain, Russian Academy of Medical Sciences.